Chronic refractory cough is a symptom that affects a significant subgroup of asthmatic patients, even when the disease is controlled. This condition negatively impacts quality of life and is often resistant to conventional asthma treatments, posing a significant clinical challenge. Despite its frequency, the pathophysiology of chronic cough in the context of adult asthma remains poorly understood and understudied. This lack of evidence hinders the development of effective and personalized therapeutic strategies. Therefore, it is essential to better characterize this entity and its possible underlying mechanisms to optimize its clinical management.
