Alpha-1 antitrypsin (AAT) deficiency is an underdiagnosed genetic disorder that predisposes individuals to the development of pulmonary emphysema and liver disease. This document establishes ten priorities for the optimal management of AAT deficiency (AATD) in […]
Introduction Hereditary transthyretin amyloidosis (vATTR) is a progressive genetic disorder with several approved treatments. We investigated treatment responses to tafamidis and patisiran in vATTR patients to identify predictive response factors. Methods Retrospective analysis on vATTR […]
Artificial intelligence (AI) has evolved from science fiction into a key tool in everyday life. In cosmetic dermatology, it has revolutionized skin assessment and the development of personalized treatments. Advanced algorithms enable the diagnosis of […]
Generalized pustular psoriasis (GPP) is an autoinflammatory disease characterized by primarily sterile pustules, with a widespread distribution, and flares that can be associated with life-threatening complications. Spesolimab (Spevigo®) is the only drug approved for treatment […]
Introduction COPD is a respiratory condition characterized by chronic airflow limitation. Exacerbations are an acute worsening of the symptoms. The objective of this study was to achieve a consensus on the management of COPD exacerbation […]
The difficulty of traditional photoprotectors in preventing actinic keratoses (AK) and keratinocyte skin cancer has led to research into new photoprotection measures. DNA repair enzymes are compounds that aim to increase the repair of DNA […]
Background and objective Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease that is difficult to manage, requiring the use of biologic drugs such as anti-TNFα and anti-interleukin 17 (anti-IL17). The aim of our review […]
Introduction To reach a multidisciplinary consensus on the management of patients with advanced COPD using Delphi methodology. Material and methods A multidisciplinary committee of experts (Pneumology, Physiotherapy, Internal Medicine, Physical Medicine and Rehabilitation, Primary Care, […]
Introduction This study explores the association between multiple sclerosis (MS) and other autoimmune diseases, including myasthenia gravis (MG), autoimmune encephalitis (AE), and demyelinating polyneuropathies such as combined central and peripheral demyelination (CCPD), chronic inflammatory demyelinating […]
Introduction Multiple sclerosis can be associated with a range of rheumatic processes. Behçet disease is a relapsing, multisystemic, immune-mediated chronic vasculitic disorder of unknown aetiology, whose symptoms overlap with those of many autoinflammatory processes. Sarcoidosis […]