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Complete Lymph Node Dissection vs Observation in Patients With Cutaneous Melanoma and Positive Sentinel Lymph Node Biopsy With High-risk Criteria: Multicenter Analysis in Hospitals in the Mediterranean Area

Background Management of patients with cutaneous melanoma and positive sentinel lymph node biopsy (SLNB) has shifted toward surveillance rather than complete lymph node dissection (CLND), because CLND has failed to demonstrate a survival benefit. However, […]

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Relevance of serum neurofilament light chain determination as a biomarker in multiple sclerosis. Consensus of the Spanish Society of Neurology’s Study Group on Multiple Sclerosis and Related Neuroimmune Diseases

Introduction Multiple sclerosis (MS) is an inflammatory, degenerative disease of the central nervous system with a complex and uncertain etiology. Although therapeutic advances have improved disease control, both prognosis and treatment monitoring continue to be […]