We report the first documented case of community-acquired pneumonia caused by Chryseobacterium gleum in an immunocompetent patient without typical risk factors. This gram-negative bacillus, historically associated with nosocomial infections in immunocompromised individuals, was identified as the etiological agent in a 73-year-old woman with respiratory sepsis. The ineffectiveness of the initial empirical treatment underscored the urgent need for precise microbiological identification. A sputum culture proved to be a crucial step, as it led to the isolation of C. gleum and revealed its resistance to several commonly used antibiotics. Guided by these findings, targeted therapy with levofloxacin proved successful, leading to the patient's complete recovery. This case demonstrates that C. gleum can be a primary pathogen in healthy individuals, underscoring the fundamental importance of obtaining microbiological cultures to guide appropriate treatment and achieve a favorable outcome, especially in infections caused by rare pathogens with intrinsic resistance profiles.