Background and objectives Evidence for secukinumab and bimekizumab in hidradenitis suppurativa (HS) primarily comes from randomized clinical trials with selected patient populations. Conversely, real-world evidence (RWE) studies reflect broader patient demographics and clinical practice. This […]
Introduction Psoriatic arthritis (PsA) is an inflammatory condition associated with psoriasis (PsO), with variable prevalence ranging from 6% to 42%. Despite the known link between PsO and PsA, reliable biomarkers for predicting PsA onset remain […]
Background Cutaneous squamous cell carcinoma (cSCC) constitutes a serious public health problem, as it is the 2nd most frequent skin cancer. Few studies have assessed epidemiological indicators of cSCC in Southern Europe. The objectives of […]
Neuroglia has an essential role in pain perception that goes beyond neuropathic pain and is now considered to play a major role in the processes of sensitization, establishment of chronic pain and nociplasticity. In this […]
Introduction Parkinson's disease (PD), a prevalent neurodegenerative disorder characterized by motor dysfunction, presents a significant therapeutic challenge due to the lack of disease-modifying treatments. Emerging evidence suggests a crucial role of the gut microbiota in […]
Introduction Hematological parameters are considered to be implicated in the pathogenesis of acute ischemic stroke. Otherwise, to our knowledge, it is still not known whether there are any differences between small and large vessel strokes, […]