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Elsevier España
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Biomarcadores en sangre para la enfermedad de Alzheimer: posicionamiento y recomendaciones de uso del Grupo de Estudio de Conducta y Demencias de la Sociedad Española de Neurología
Introducción El desarrollo de biomarcadores en sangre para detectar la enfermedad de Alzheimer (EA) representa uno de los avances recientes más significativos y algunos ya están disponibles para la práctica clínica. Por ello, el Grupo […]
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Late-onset Rasmussen encephalitis: 3 illustrative cases and a review of the literature
Introduction Late-onset Rasmussen encephalitis (LORE) is a rare, unihemispheric, progressive, inflammatory disorder causing severe neurological dysfunction and drug-resistant epilepsy with onset during late adolescence or adulthood. Due to the scarcity of available evidence, this study […]
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Understanding stroke mortality trends in Spain: A comprehensive age-period-cohort and joinpoint analysis
Background This study aims to update and evaluate the age-period-cohort (A-P-C) effects on stroke mortality in Spain over the period 1982–2021. Methods Data on stroke mortality and population by age and sex were obtained from […]
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Left atrial appendage closure in patients with prior intracranial bleeding, safety, efficacy, and timing
Background Oral anticoagulation (OAC) use increases the risk of intracranial hemorrhage (ICH) in patients with atrial fibrillation (AF) and CHA2DS2-VASc ≥2. Left atrial appendage occlusion (LAAO) is an alternative to OAC, however data about its […]
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Manejo actual de las crisis epilépticas urgentes en un hospital de tercer nivel de la Comunidad de Madrid, estudio descriptivo
Objetivo Analizar el estado actual del manejo de las crisis epilépticas (CE) urgentes en un hospital de tercer nivel de la Comunidad de Madrid en cada etapa del proceso asistencial y por parte de los […]
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Desarrollo y validación concurrente de un instrumento retrogenético para la valoración de las actividades de la vida diaria: la Escala de Evaluación Funcional del Test Barcelona
Introducción La valoración de las actividades de la vida diaria (AVD) se considera esencial en la evaluación del deterioro cognitivo leve (DCL), la demencia y para su correcto diagnóstico diferencial. Existen muchas escalas para la […]
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Periodontal disease and brain amyloid pathology in mild cognitive impairment
Introduction Increases in brain β-amyloid protein (Aβ) levels have been demonstrated in animal models following oral inoculation of periodontopathogens or their enzyme gingipain. We investigated the association between periodontitis and brain Aβ protein levels in […]
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Redefining periodic paralysis with CACNA1S mutation in a Spanish cohort
Introduction Muscle MRI and electrophysiological exercise testing have been reported as useful techniques in hypokalemic periodic paralysis (HypoPP). Striking clinical differences between men and women with this disorder are well known; however, little information is […]
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Effect of sex on the progression of non-motor symptoms in Parkinson’s disease: A registry-based cohort study
Introduction Differences in the trajectory of non-motor symptoms (NMS) between male and female Parkinson's disease (PD) patients over the course of the disease are not well-understood. Methods PD patients were rated with Non-Motor Symptom Scale […]