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Immune checkpoint inhibitors (ICIs) have significantly advanced the treatment of cancer. They are not, however, free of adverse effects. These effects are called immune-related adverse events (irAEs) and often involve the skin. Most of the […]
Real-World Evidence of Adjuvant Immunotherapy in Resected Stage III and IV Melanoma Patients: CADIM Trial Final Results. Experience From 2 Tertiary Referral Centers
Introduction Clinical trials have validated the use of nivolumab and pembrolizumab as adjuvant therapies regarding relapse-free survival in patients with resected stage III and IV melanoma. Evidence in real-world patients is currently limited. Material and […]
Exonic variants of the P2RX7 gene in familial multiple sclerosis
Introduction Several studies have analysed the presence of P2RX7 variants in patients with MS, reporting diverging results. Methods Our study analyses P2RX7 variants detected through whole-exome sequencing (WES). Results We analysed P2RX7, P2RX4, and CAMKK2 […]
